PET Radiochemistry
WMIC has an active radiotracer development programme which aims to expand our portfolio of available tracers. This programme uses our extensive radiochemistry facilities to produce to GMP standards for clinical studies as well as experimental tracers for pre-clinical studies.
If you would like to discuss any of the radiotracers shown in the table below, or other possibilities, please contact Gavin Brown.
| Tracer | Used to study | Status |
|---|---|---|
| [15O] Water | Blood flow | GMP online |
| [15O] Carbon Monoxide | Blood volume | GMP online |
| [18F] FDG | Glucose metabolism | GMP online |
| [11C] PK11195 | Peripheral benzodiazepine binding site | GMP online |
| [11C] MDL 100,907 | Serotonin 5-HT2A receptor | GMP online |
| [11C] DASB | Serotonin transporter | GMP online |
| [11C] Antisense compound | Apoptosis | GMP online |
| [18F] FLT | Proliferation | GMP online |
| [11C] Methionine | Protein synthesis | GMP online |
| [11C] Verapamil | P-glycoprotein transporter | GMP online |
| [18F] Proprietory amyloid tracer | Amyloid plaque | GMP online |
| [11C] Diprenorphine | Non-subtype selective opiate receptor | GMP online |
| [18F] labelling of generic macromolecules | Various | non-GMP online |
| [18F] DPA-713/714 | Peripheral benzodiazepine binding site | non-GMP online |
| [18F] Interleukin-1RA | Neuro-inflammation | non-GMP online |
| [18F] F-DOPA | Dopamine synthesis | GMP online |
| [18F] MISO | Hypoxia | In development |
| [18F] Fluorocholine | Cellular phospholipid synthesis | GMP online |
| [18F] Sodium Fluoride | Bone scanning | GMP online |
Some of our tracers are available for distribution. For more information please contact Jonathan Bevan.
